Description

Benzonitrile, 4-Fluoro-2-Methoxy-5-Methyl- (9Ci) is a high-purity, multi-substituted aromatic nitrile building block of significant interest in advanced organic synthesis. Its unique molecular structure, featuring fluorine, methoxy, and methyl substituents, makes it a versatile precursor for creating complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for constructing fluorinated drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound research.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides where the fluorine atom enhances biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a building block for advanced electronic materials, where its substituted benzonitrile core contributes to desired mesogenic or electroluminescent properties.
• Organic Synthesis & Catalysis: Employed in cross-coupling reactions (e.g., Suzuki, Sonogashira) and as a ligand precursor in transition metal catalysis due to the nitrile functionality.
• Chemical Research & Development: A valuable reference standard and starting material in academic and industrial R&D for exploring new synthetic methodologies and structure-activity relationships (SAR).

Basic Information

Product Name	Benzonitrile, 4-Fluoro-2-Methoxy-5-Methyl- (9Ci)
CAS No.	314298-16-3
Molecular Formula	C9H8FNO
Molecular Weight	165.16 g/mol
Synonyms	4-Fluoro-2-methoxy-5-methylbenzonitrile; 5-Methyl-2-methoxy-4-fluorobenzonitrile; 2-Methoxy-4-fluoro-5-methylbenzonitrile; 4-Fluoro-5-methyl-2-methoxybenzonitrile; 2-Methoxy-5-methyl-4-fluorobenzonitrile; Benzonitrile, 4-fluoro-2-methoxy-5-methyl-; 4-Fluoro-2-methoxy-5-methylbenzenecarbonitrile
EINECS	Contact for details

Quality Control

Our Benzonitrile, 4-Fluoro-2-Methoxy-5-Methyl- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, confirming compliance with customer specifications and relevant industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Standard Grade)
Purity (GC)	≥97.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.