Description

3-Bromo-5-Fluorophenylacetonitrile is a versatile halogenated aromatic nitrile building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both bromine and fluorine substituents, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and insecticides, where the bromo-fluoro substitution pattern can enhance biological activity and environmental profile.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in transition metal catalysis, such as cross-coupling reactions.
• Material Science Research: Employed in the creation of organic electronic materials, liquid crystals, and advanced polymers where specific halogen interactions are required.
• Custom Synthesis & Contract Manufacturing: A valuable scaffold for custom chemical synthesis services catering to R&D projects requiring specific halogenated aromatic architectures.

Basic Information

Product Name	3-Bromo-5-Fluorophenylacetonitrile
CAS No.	305800-58-2
Molecular Formula	C8H5BrFN
Molecular Weight	214.04 g/mol
Synonyms	(3-Bromo-5-fluorophenyl)acetonitrile; 2-(3-Bromo-5-fluorophenyl)acetonitrile; 3-Bromo-5-fluorobenzyl cyanide; α-Cyano-3-bromo-5-fluorotoluene; 305800-58-2; 3-Bromo-5-fluoro-benzeneacetonitrile; 3-Bromo-5-fluorophenylacetonitrile; (3-Bromo-5-fluorophenyl)ethanenitrile
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-Fluorophenylacetonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding synthesis projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases, strong oxidizing agents, and sources of ignition. The compound may be moisture-sensitive; keep container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.