Description

11Beta,17,21-Trihydroxypregna-1,4-Diene-3,20-Dione 21-Valerate is a synthetic corticosteroid derivative, specifically a valerate ester of a prednisolone analog. This compound is a key pharmaceutical intermediate of significant commercial value, primarily used in the research and development of advanced anti-inflammatory and immunosuppressive medications. It is essential for manufacturers and R&D laboratories in the pharmaceutical and fine chemical sectors seeking to produce or investigate novel steroid-based therapeutics.

Application

• Pharmaceutical Intermediate: Primary use in the synthesis of potent topical and systemic corticosteroid APIs (Active Pharmaceutical Ingredients).
• Anti-inflammatory Drug Research: Serves as a critical building block in the development of new drugs for treating conditions like dermatitis, psoriasis, and arthritis.
• Immunosuppressant Development: Used in research programs aimed at creating agents to manage autoimmune diseases and prevent organ transplant rejection.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and impurity profiling.
• Biochemical Research: Utilized in academic and industrial studies investigating glucocorticoid receptor activity and steroid metabolism.

Basic Information

Product Name	11Beta,17,21-Trihydroxypregna-1,4-Diene-3,20-Dione 21-Valerate
CAS No.	39791-31-6
Molecular Formula	C26H36O7
Molecular Weight	460.56 g/mol
Synonyms	Prednisolone 21-Valerate; 11β,17,21-Trihydroxypregna-1,4-diene-3,20-dione 21-valerate; 21-Valerylprednisolone; Betamethasone 17-valerate related compound; NSC 106977; Pregna-1,4-diene-3,20-dione, 11,17,21-trihydroxy-, 21-(1-oxopentyl)-, (11β)-; 11β-Hydroxyprednisolone 21-valerate
EINECS	Contact for details

Quality Control

Our 11Beta,17,21-Trihydroxypregna-1,4-Diene-3,20-Dione 21-Valerate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical intermediates. Certificates of Analysis (COA) detailing all test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.