Description

17,21-Dihydroxy-16Beta-Methylpregna-1,4,9(11)-Triene-3,20-Dione 21-Benzoate is a high-purity steroid derivative, specifically a benzoate ester of a modified pregnane triene structure. This compound is valued for its role as a critical pharmaceutical intermediate in the synthesis of advanced steroid-based active pharmaceutical ingredients (APIs). It is primarily required by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of potent corticosteroid and other steroid-based APIs.
• Research & Development: Used in medicinal chemistry research for structure-activity relationship (SAR) studies and the development of new drug candidates.
• Reference Standard: Serves as a certified reference material (CRM) for analytical method development, validation, and quality control in pharmaceutical laboratories.
• Process Chemistry: Employed in scale-up and process optimization for the commercial manufacturing of steroid drugs.

Basic Information

Item	Details
Product Name	17,21-Dihydroxy-16Beta-Methylpregna-1,4,9(11)-Triene-3,20-Dione 21-Benzoate
CAS No.	39780-55-7
Molecular Formula	C29H34O5
Molecular Weight	462.58 g/mol
Synonyms	16β-Methylpregna-1,4,9(11)-triene-17,21-diol-3,20-dione 21-benzoate; 21-Benzoyloxy-16β-methylpregna-1,4,9(11)-triene-3,20-dione-17-ol; 16β-Methyl-9(11)-dehydroprednisolone 21-benzoate; Prednisolone 21-benzoate derivative; 9(11)-Dehydro-16β-methylprednisolone 21-benzoate; 16β-Methyl-δ9(11)-prednisolone 21-benzoate
EINECS	Contact for details

Quality Control

Our 17,21-Dihydroxy-16Beta-Methylpregna-1,4,9(11)-Triene-3,20-Dione 21-Benzoate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the stringent requirements for pharmaceutical intermediates. Certificates of Analysis (COA) with full traceability are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled and stored away from direct light exposure to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.