Description

17,21-Dihydroxy-16Beta-Methylpregna-4,9(11)-Diene-3,20-Dione 21-Benzoate is a high-purity steroid intermediate of significant importance in pharmaceutical synthesis. This compound matters because it serves as a critical building block for the development of advanced steroidal active pharmaceutical ingredients (APIs). Pharmaceutical manufacturers and advanced research organizations need this precise intermediate for its role in creating potent therapeutic agents, particularly in specialized hormonal and anti-inflammatory drug development pipelines.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of potent corticosteroid and other steroidal APIs.
• Research & Development: Used in medicinal chemistry for the discovery and optimization of new steroidal drug candidates with targeted biological activity.
• Process Chemistry: Employed in scaling up and optimizing manufacturing routes for complex steroid molecules in GMP environments.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.
• Biochemical Research: Utilized in studies investigating steroid hormone receptor interactions and metabolic pathways.

Basic Information

Product Name	17,21-Dihydroxy-16Beta-Methylpregna-4,9(11)-Diene-3,20-Dione 21-Benzoate
CAS No.	39780-54-6
Molecular Formula	C29H36O5
Molecular Weight	464.60 g/mol
Synonyms	16β-Methylprednisolone 21-Benzoate; 16β-Methyl-δ9-prednisolone 21-Benzoate; 21-Benzoyloxy-16β-methylpregna-4,9(11)-diene-3,20-dione-17α-ol; 17α,21-Dihydroxy-16β-methylpregna-4,9(11)-diene-3,20-dione 21-benzoate; 16β-Methyl-9-dehydroprednisolone 21-benzoate; 9-Dehydro-16β-methylprednisolone 21-benzoate
EINECS	Contact for details

Quality Control

Our 17,21-Dihydroxy-16Beta-Methylpregna-4,9(11)-Diene-3,20-Dione 21-Benzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical intermediate applications. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a low-humidity environment to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.