Description

Picumast is a selective phosphodiesterase 4 (PDE4) inhibitor with significant anti-inflammatory and immunomodulatory properties. This compound is valued for its targeted mechanism of action, which makes it a key intermediate in advanced pharmaceutical research and development. It is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery of novel therapeutics for inflammatory and autoimmune conditions.

Application

• Pharmaceutical intermediate for the synthesis of advanced anti-inflammatory drug candidates.
• Key building block in preclinical research targeting PDE4-mediated pathways.
• Reference standard for analytical method development and quality control in API manufacturing.
• Biochemical tool for studying cellular signaling mechanisms in immunology research.
• Potential starting material for developing treatments for chronic obstructive pulmonary disease (COPD) and asthma.
• Used in investigative studies for dermatological conditions like psoriasis and atopic dermatitis.

Basic Information

Product Name	Picumast
CAS No.	39577-20-3
Molecular Formula	C₁₉H₂₀N₂O₃
Molecular Weight	324.38 g/mol
Synonyms	PDE4 Inhibitor Picumast; 8-Amino-1,3-bis(cyclopropylmethyl)xanthine; 8-Amino-1,3-dicyclopropylmethyl-3,7-dihydro-1H-purine-2,6-dione; ZK 62711; Picumast Dihydrochloride (salt form); 1H-Purine-2,6-dione, 8-amino-1,3-bis(cyclopropylmethyl)-3,7-dihydro-
EINECS	Contact for details

Quality Control

Our Picumast is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation. A detailed Certificate of Analysis (COA) documenting all specifications is provided with every shipment to support your research and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.