Description

Cloranolol CAS NO 39563-28-5 is a selective β-adrenergic receptor antagonist (β-blocker) used in pharmaceutical research and development. This compound is critical for studying cardiovascular pharmacology and developing new therapeutic agents for conditions such as hypertension and angina. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and fine chemical manufacturers focused on active pharmaceutical ingredient (API) synthesis.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of advanced β-blocker APIs.
• Biochemical Research: Tool compound for studying β-adrenergic receptor mechanisms and signal transduction pathways.
• Cardiovascular Drug Development: Used in preclinical research for developing new antihypertensive and antianginal medications.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.
• Metabolite Studies: Employed in pharmacokinetic and metabolic profiling studies of related β-blocker drugs.

Basic Information

Item	Details
Product Name	Cloranolol
CAS No.	39563-28-5
Molecular Formula	C16H23ClN2O3
Molecular Weight	338.82 g/mol
Synonyms	1-(4-Chlorophenoxy)-3-[(1-methylethyl)amino]-2-propanol; (±)-1-(4-Chlorophenoxy)-3-(isopropylamino)-2-propanol; Cloranololum; Cloranolol Hydrochloride (salt form); SC-27761; ICI 66082; 4'-(2-Hydroxy-3-isopropylaminopropoxy)chlorobenzene
EINECS	Contact for details

Quality Control

Our Cloranolol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, residual solvent analysis, and identity confirmation by FT-IR and NMR to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with complete traceability are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using a desiccant.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.5%
Any single unknown impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.