Description

17,21-Dihydroxypregna-1,4-Diene-3,11,20-Trione 21-Hexadecanoate is a high-purity steroid derivative, specifically a palmitate ester of a dihydroxypregnadienetrione. This compound is a critical advanced intermediate in the synthesis of complex steroid-based active pharmaceutical ingredients (APIs) and fine chemicals. It is essential for research and development laboratories and production facilities in the pharmaceutical and biotechnology sectors, where precise chemical structure and purity are paramount for successful outcomes.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of potent corticosteroid APIs and other therapeutic steroid molecules.
• Biochemical Research: Used as a reference standard or precursor in metabolic pathway studies, receptor binding assays, and hormonal research.
• Fine Chemical Synthesis: Serves as a specialized starting material for creating novel steroid analogs with potential biological activity in academic and industrial R&D.
• Process Development: Employed in scaling up and optimizing synthetic routes for steroid production within GMP and non-GMP environments.

Basic Information

Product Name	17,21-Dihydroxypregna-1,4-Diene-3,11,20-Trione 21-Hexadecanoate
CAS No.	39007-81-3
Molecular Formula	C37H56O6
Molecular Weight	596.85 g/mol
Synonyms	Prednisolone 21-Palmitate; 21-Palmitoylprednisolone; Prednisolone Palmitate; 11β,17α,21-Trihydroxypregna-1,4-diene-3,20-dione 21-hexadecanoate; 17,21-Dihydroxypregna-1,4-diene-3,11,20-trione 21-palmitate; NSC 106977; 1,4-Pregnadiene-11β,17α,21-triol-3,20-dione 21-palmitate
EINECS	Contact for details

Quality Control

Our 17,21-Dihydroxypregna-1,4-Diene-3,11,20-Trione 21-Hexadecanoate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and synthesis. Quality is verified through comprehensive analytical techniques including HPLC, NMR, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with each batch, confirming identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.