Description

Butecort CAS NO 38965-31-0 is a synthetic corticosteroid derivative, specifically a 21-acetate ester of prednisolone. This compound is a key pharmaceutical intermediate of significant commercial importance, primarily used in the synthesis of more complex steroid-based active pharmaceutical ingredients (APIs). It is essential for manufacturers in the pharmaceutical and fine chemical sectors who require high-purity, reliable building blocks for producing anti-inflammatory and immunosuppressive medications.

Application

• Pharmaceutical Intermediate: Primary use as a crucial building block in the multi-step synthesis of potent topical and systemic corticosteroids.
• API Synthesis: Serves as a precursor in the manufacturing of advanced steroid-based Active Pharmaceutical Ingredients (APIs) for anti-inflammatory drugs.
• Research & Development: Used in pharmaceutical R&D laboratories for exploring new steroid derivatives and metabolic pathways.
• Veterinary Medicine: Potential application in the development of anti-inflammatory treatments for veterinary use.
• Reference Standard: Can be utilized as an analytical reference standard in quality control laboratories for method development and validation.

Basic Information

Product Name	Butecort
CAS No.	38965-31-0
Molecular Formula	C26H34O7
Molecular Weight	458.55 g/mol
Synonyms	Prednisolone 21-Acetate; 11β,17α,21-Trihydroxypregna-1,4-diene-3,20-dione 21-Acetate; (11β)-11,17,21-Trihydroxypregna-1,4-diene-3,20-dione 21-acetate; Butecort; Prednisolone Acetate (specifically the 21-ester); 1,4-Pregnadiene-3,20-dione, 11,17,21-trihydroxy-, 21-acetate, (11β)-; NSC 132319
EINECS	Contact for details

Quality Control

Our Butecort is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets exacting standards suitable for pharmaceutical intermediate use. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.