Description

n-Butyryldaunorubicin is a semi-synthetic anthracycline derivative, specifically an ester analog of the well-known chemotherapeutic agent daunorubicin. This compound is primarily valued in pharmaceutical research and development for its role as a key intermediate in the synthesis of advanced anticancer agents and for studying structure-activity relationships. It is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors focused on oncology drug discovery and the production of novel chemotherapeutic formulations.

Application

• Pharmaceutical Intermediate: Critical precursor in the synthesis of novel anthracycline-based chemotherapeutic drugs.
• Oncology Research: Used in biochemical and pharmacological studies to investigate mechanisms of action, cytotoxicity, and drug resistance.
• Structure-Activity Relationship (SAR) Studies: Key compound for modifying the daunorubicin molecule to develop analogs with improved efficacy or reduced side effects.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Bioconjugation Studies: Utilized in research exploring antibody-drug conjugates (ADCs) or other targeted drug delivery systems.
• Academic and Institutional Research: Employed in university and research institute labs for fundamental cancer research and drug discovery projects.

Basic Information

Product Name	n-Butyryldaunorubicin
CAS No.	38942-41-5
Molecular Formula	C₃₂H₃₅NO₁₂
Molecular Weight	625.62 g/mol
Synonyms	Daunorubicin 13-butyrate; 13-O-Butyryldaunorubicin; Daunorubicin butyrate; Butyryldaunomycin; 4'-Demethoxy-7-O-(3,5-dideoxy-5-aminoglycopyranosyl)adriamycinone 13-butyrate; NSC 357704; AD 32 (a related analog, often referenced); Cerubidine butyrate ester
EINECS	Contact for details

Quality Control

Our n-Butyryldaunorubicin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by spectroscopic methods (IR, NMR, MS), and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade specifications. For custom synthesis or specific purity requirements (e.g., >98%, >99%), please contact our technical team.

Storage

Preserve in a tightly closed container, protected from light. Store in a freezer at -20°C or below. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Allow the sealed container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	Orange to red powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (IR)	Spectrum matches reference
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.