Description

3-[4-[2-Hydroxy-3-(Propan-2-Ylamino)Propoxy]Phenyl]-1-Methyl-Urea is a specialized organic compound primarily used as a key pharmaceutical intermediate. Its molecular structure, featuring a urea core linked to a phenoxypropanolamine moiety, makes it a critical building block in the synthesis of advanced active pharmaceutical ingredients (APIs). This high-purity intermediate is essential for research institutions and pharmaceutical manufacturers engaged in the development and production of targeted therapeutics.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of β-adrenergic blocking agents (β-blockers) and other cardiovascular APIs.
• Research & Development: Serves as a key starting material (KSM) or advanced intermediate in medicinal chemistry for novel drug discovery programs.
• Active Pharmaceutical Ingredient (API) Manufacturing: Used in the controlled synthesis of final drug substances under current Good Manufacturing Practice (cGMP) conditions.
• Chemical Synthesis: Employed in organic synthesis for constructing complex molecules with specific biological activity, particularly those targeting adrenergic receptors.
• Reference Standard: Can be supplied as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.

Basic Information

Product Name	3-[4-[2-Hydroxy-3-(Propan-2-Ylamino)Propoxy]Phenyl]-1-Methyl-Urea
CAS No.	38649-68-2
Molecular Formula	C14H23N3O3
Molecular Weight	281.35 g/mol
Synonyms	1-Methyl-3-[4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]phenyl]urea; Carazolol Impurity; Carazolol Related Compound; Urea, N-methyl-N'-[4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]phenyl]-; BM 51052; BM-51052; BM51052; (RS)-1-(4-[2-Hydroxy-3-(isopropylamino)propoxy]phenyl)-3-methylurea
EINECS	Contact for details

Quality Control

Our 3-[4-[2-Hydroxy-3-(Propan-2-Ylamino)Propoxy]Phenyl]-1-Methyl-Urea is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity, suitable for pharmaceutical applications. We provide comprehensive analytical data and can supply material that meets in-house specifications or custom purity requirements. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available for every batch.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.