Description

Penbutolol Sulfate (200 Mg) is a high-purity, non-selective β-adrenergic blocking agent in its sulfate salt form. This compound is critical for pharmaceutical research and development, particularly in the study of cardiovascular pharmacology and the formulation of reference standards. It is primarily utilized by pharmaceutical manufacturers, analytical laboratories, and research institutions engaged in drug discovery, quality control, and clinical studies related to hypertension and angina.

Application

• Pharmaceutical Active Ingredient (API): Used in the research and development of β-blocker medications for cardiovascular conditions.
• Reference Standard: Serves as a certified reference material (CRM) for analytical method development, validation, and quality control testing in laboratories.
• Biochemical Research: Employed in preclinical studies to investigate β-adrenergic receptor mechanisms and cardiovascular physiology.
• Formulation Development: A key component in the development of solid dosage forms, such as tablets, for clinical trials.
• Impurity Profiling: Used as a marker or standard in HPLC and other chromatographic systems to identify and quantify related substances.

Basic Information

Product Name	Penbutolol Sulfate (200 Mg)
CAS No.	38363-32-5
Molecular Formula	C18H29NO2 · H2SO4
Molecular Weight	403.50 g/mol (free base: 291.43 g/mol)
Synonyms	Penbutolol Sulphate; (S)-1-(tert-Butylamino)-3-(2-cyclopentylphenoxy)propan-2-ol Sulfate; Hoe 39d; Hoe-39d; Levobunolol related compound A (sulfate salt); (+)-Penbutolol Sulfate; Betapressin Sulfate
EINECS	Contact for details

Quality Control

Our Penbutolol Sulfate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, assay, and impurity profiling, to ensure it meets high-purity standards suitable for pharmaceutical research. A detailed Certificate of Analysis (COA) with full chromatographic data is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0% (on anhydrous basis)
Water Content (KF)	≤2.0%
Related Substances (HPLC)	Total impurities ≤2.0% Any single impurity ≤0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.