Description

(R)-5,6,6A,7-Tetrahydro-1,2,9,10-Tetramethoxy-6-Methyl-4H-Dibenzo[De,G]Quinoline CAS NO 38325-02-9 is a high-purity, chiral tetrahydroisoquinoline alkaloid derivative, distinguished by its specific (R)-enantiomeric configuration. This compound serves as a critical advanced intermediate in pharmaceutical research and development, particularly for the synthesis of complex bioactive molecules. It is essential for medicinal chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries seeking to develop novel therapeutics or study structure-activity relationships.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of potential drug candidates targeting neurological and cardiovascular systems.
• Medicinal Chemistry Research: Used in the exploration of structure-activity relationships (SAR) for alkaloid-based compounds.
• Asymmetric Synthesis: Serves as a sophisticated starting material or intermediate in catalytic asymmetric transformations.
• Reference Standard: High-purity material for analytical method development, validation, and quality control in regulatory submissions.
• Biochemical Tool Compound: Potential use in pharmacological studies to investigate specific receptor interactions or enzymatic pathways.
• Fine Chemical Synthesis: Intermediate for the production of other complex, high-value specialty chemicals.

Basic Information

Product Name	(R)-5,6,6A,7-Tetrahydro-1,2,9,10-Tetramethoxy-6-Methyl-4H-Dibenzo[De,G]Quinoline
CAS No.	38325-02-9
Molecular Formula	C22H27NO4
Molecular Weight	369.46 g/mol
Synonyms	(R)-Bulbocapnine; (R)-Bulbocapnine derivative; (6R)-5,6,6a,7-Tetrahydro-1,2,9,10-tetramethoxy-6-methyl-4H-dibenzo[de,g]quinoline; (R)-6-Methyl-1,2,9,10-tetramethoxy-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline; NSC 336579; (R)-enantiomer of Bulbocapnine precursor; Tetramethoxy-tetrahydro-dibenzoquinoline derivative
EINECS	Contact for details

Quality Control

Our (R)-5,6,6A,7-Tetrahydro-1,2,9,10-Tetramethoxy-6-Methyl-4H-Dibenzo[De,G]Quinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥97.0%
Chiral Purity (Chiral HPLC)	≥98.0% (R)-enantiomer
Related Substances (HPLC)	Total impurities ≤3.0% Any single impurity ≤1.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.