Description

S-Bupranolol is a high-purity, non-selective β-adrenergic receptor antagonist (β-blocker) of significant pharmaceutical interest. This compound is valued for its stereochemical purity, which is critical for research into cardiovascular pharmacology and the development of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D departments, fine chemical manufacturers, and academic research institutions focused on adrenergic signaling pathways and drug discovery.

Application

• Pharmaceutical Reference Standard: Serves as a certified analytical standard for quality control and method validation in drug manufacturing.
• Active Pharmaceutical Ingredient (API) Intermediate: A key chiral building block in the synthesis of advanced β-blocker medications.
• Biochemical Research: Used in in vitro and in vivo studies to investigate β-adrenergic receptor function and antagonism.
• Metabolite Studies: Employed in pharmacokinetic and metabolic pathway research for related pharmaceutical compounds.
• Process Development: Acts as a model compound for developing and optimizing chiral synthesis and purification processes.

Basic Information

Product Name	S-Bupranolol
CAS No.	38104-34-6
Molecular Formula	C14H22N2O2
Molecular Weight	250.34 g/mol
Synonyms	(S)-Bupranolol; (S)-1-(tert-Butylamino)-3-(2-chloro-5-methylphenoxy)propan-2-ol; Levobunolol Related Compound A; (-)-Bupranolol; S-(-)-Bupranolol; Bupranolol Impurity A; 1-[(1,1-Dimethylethyl)amino]-3-[(2-chloro-5-methylphenoxy)]-2-propanol, (S)-
EINECS	Contact for details

Quality Control

Our S-Bupranolol is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including chiral purity determination by HPLC, to ensure it meets stringent specifications for research and development use. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (Enantiomeric Excess)	≥99.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.