Description

Tolamolol CAS NO 38103-61-6 is a selective β-adrenergic receptor antagonist (β-blocker) of significant pharmaceutical interest. This compound is a key intermediate in the research and development of cardiovascular therapeutics, offering a critical building block for medicinal chemistry. It is primarily utilized by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in the synthesis of novel active pharmaceutical ingredients (APIs) and pharmacological studies.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of advanced β-blocker drug candidates and related cardiovascular agents.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies to develop new therapeutic molecules with optimized efficacy and safety profiles.
• Reference Standard: Used as an analytical standard in quality control laboratories for method development, validation, and impurity profiling in pharmaceutical manufacturing.
• Biochemical Research: Employed in pharmacological assays to study β-adrenergic receptor binding, selectivity, and signal transduction mechanisms.
• Process Development: Utilized in scaling up and optimizing synthetic routes for the cost-effective production of target drug substances.

Basic Information

Product Name	Tolamolol
CAS No.	38103-61-6
Molecular Formula	C17H20N2O3
Molecular Weight	300.35 g/mol
Synonyms	4-[2-Hydroxy-3-[(2-methyl-1-indanyl)oxy]propyl]morpholine; Tolamololum; Tolamolol Hydrochloride (salt form); B 24/76; MJ 1999; (±)-Tolamolol; DL-Tolamolol; 1-(Indan-2-yloxy)-3-(morpholin-4-yl)propan-2-ol
EINECS	Contact for details

Quality Control

Our Tolamolol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identity confirmation, purity assay, and impurity profiling, to ensure it meets the stringent requirements for pharmaceutical research and development. Certificates of Analysis (COA) detailing all test results are provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.