Description

9-Fluoro-11,17-Dihydroxy-21-Diiodo-16-Methylpregna-1,4-Diene-3,20-Dione 9-Fluoro-21-Di-Iodo-16-Methylpregna-1,4-Diene-11,17-Diol-3,20-Dione CAS NO 37414-01-0 is a high-purity, fluorinated and iodinated steroid derivative, serving as a critical advanced pharmaceutical intermediate for research and development. Its complex structure makes it a valuable precursor for synthesizing novel corticosteroid analogs with potential therapeutic applications. This compound is essential for pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing next-generation anti-inflammatory and immunosuppressive agents.

Application

• Pharmaceutical Intermediate: Key building block in the research and synthesis of novel fluorinated corticosteroid drugs.
• Biochemical Research: Used as a reference standard or probe in steroid receptor binding studies and metabolic pathway investigations.
• Process Development: Serves as a critical intermediate for optimizing synthetic routes for complex steroid-based active pharmaceutical ingredients (APIs).
• Academic Research: Utilized in universities and research institutes for studying structure-activity relationships (SAR) in steroid chemistry.
• Custom Synthesis: Starting material for the contract manufacturing of specialized steroid derivatives for clinical trials.

Basic Information

Item	Details
Product Name	9-Fluoro-11,17-Dihydroxy-21-Diiodo-16-Methylpregna-1,4-Diene-3,20-Dione
CAS No.	37414-01-0
Molecular Formula	C22H27F I2O4
Molecular Weight	620.26 g/mol
Synonyms	9-Fluoro-21-Di-Iodo-16-Methylpregna-1,4-Diene-11,17-Diol-3,20-Dione; 9α-Fluoro-11β,17α,21-Trihydroxy-16α-methylpregna-1,4-diene-3,20-dione 21-Diiodoacetate; 21-Diiodo-9α-fluoro-11β,17α-dihydroxy-16α-methylpregna-1,4-diene-3,20-dione; 9α-Fluoro-11β,17α-dihydroxy-16α-methyl-21-(diiodoacetyl)pregna-1,4-diene-3,20-dione; 9-Fluoro-11,17-Dihydroxy-21-Diiodo-16-Methylpregna-1,4-Diene-3,20-Dione; 9-Fluoro-21-Diiodo-16-Methylpregna-1,4-Diene-11,17-Diol-3,20-Dione
EINECS	Contact for details

Quality Control

Our 9-Fluoro-11,17-Dihydroxy-21-Diiodo-16-Methylpregna-1,4-Diene-3,20-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS). We provide comprehensive Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics to ensure it meets the stringent requirements for pharmaceutical R&D. Specifications can be aligned with client-specific protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.