Description

Pargolol (Hydrochloride) is a high-purity pharmaceutical intermediate and research chemical. This compound is critical for the development and synthesis of advanced β-adrenergic blocking agents. It is primarily utilized by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic research institutions engaged in cardiovascular drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of β-blocker (β-adrenergic antagonist) active pharmaceutical ingredients (APIs).
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the development of new cardiovascular therapeutics.
• Reference Standard: Serves as an analytical standard for quality control and method validation in pharmaceutical manufacturing.
• Process Chemistry: Employed in scale-up and optimization of synthetic routes for related pharmacologically active compounds.
• Biochemical Research: Used as a tool compound in pharmacological studies to investigate adrenergic receptor interactions and signaling pathways.

Basic Information

Product Name	Pargolol (Hydrochloride)
CAS No.	36902-82-6
Molecular Formula	C₁₆H₂₆N₂O₃ • HCl
Molecular Weight	330.85 g/mol
Synonyms	Pargolol HCl; 1-(tert-Butylamino)-3-[(5,6,7,8-tetrahydro-1-naphthyl)oxy]-2-propanol Hydrochloride; (±)-Pargolol Hydrochloride; Pargolol Hydrochloride; 1-(1,1-Dimethylethyl)amino-3-[(5,6,7,8-tetrahydro-1-naphthalenyl)oxy]-2-propanol Hydrochloride; 2-Propanol, 1-[(1,1-dimethylethyl)amino]-3-[(5,6,7,8-tetrahydro-1-naphthalenyl)oxy]-, hydrochloride (1:1); Pargololum Hydrochloride
EINECS	Contact for details

Quality Control

Our Pargolol (Hydrochloride) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling via HPLC, to ensure it meets stringent specifications for research and pharmaceutical use. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Related Substances (HPLC)	Individual impurity: ≤0.5%; Total impurities: ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.