Description

Zorubicin Hcl CAS NO 36508-71-1 is a hydrochloride salt form of Zorubicin, an anthracycline antibiotic derivative. This compound is a critical pharmaceutical intermediate and active pharmaceutical ingredient (API) primarily used in oncology research and development. It is essential for researchers and manufacturers developing chemotherapeutic agents targeting specific cancer cell lines. Professionals in the pharmaceutical, biotechnology, and advanced life science sectors require this high-purity chemical for synthesis and investigative studies.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of advanced anthracycline-based chemotherapeutic agents.
• Oncology Research: Used as a reference standard and active compound in preclinical studies to investigate mechanisms of action, efficacy, and cytotoxicity against various cancer models.
• Active Pharmaceutical Ingredient (API): Employed in the formulation development of injectable chemotherapeutic drugs under strict Good Manufacturing Practice (GMP) guidelines.
• Biochemical Research: Utilized in studies exploring DNA intercalation, topoisomerase II inhibition, and the generation of reactive oxygen species in cellular systems.
• Analytical Standard: Functions as a high-purity certified reference material (CRM) for quality control and assay development in pharmaceutical laboratories.
• Academic & Institutional Research: Supports fundamental research in medicinal chemistry and pharmacology within universities and government research institutes.

Basic Information

Product Name	Zorubicin Hcl
CAS No.	36508-71-1
Molecular Formula	C₃₀H₃₅NO₁₂ • HCl
Molecular Weight	638.06 g/mol (for free base, HCl salt to be confirmed)
Synonyms	Zorubicin Hydrochloride; RP-22050; NSC-382577; 3'-Deamino-3'-(4-morpholinyl)doxorubicin Hydrochloride; (7S,9S)-9-Acetyl-7-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione Hydrochloride; Rubidazone Hydrochloride; Daunorubicin 3'-(N-Morpholino) Derivative Hydrochloride
EINECS	Contact for details

Quality Control

Our Zorubicin Hcl is produced and tested to meet the stringent requirements for pharmaceutical intermediates and reference standards. Each batch undergoes comprehensive analytical testing including HPLC for purity and related substances, identity confirmation by IR and MS, residual solvent analysis, and specific tests for water content. We adhere to a robust quality management system. Certificates of Analysis (COA) with detailed chromatograms and full traceability are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C) or as specified on the label. This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Orange to red powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥97.0% (anhydrous basis)
Related Substances (HPLC)	Total impurities ≤3.0% Any single unknown impurity ≤1.0%
Water Content (KF)	≤5.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.