Description

2-Bromo-4-Fluorobenzonitrile is a versatile halogenated aromatic nitrile building block of significant importance in advanced organic synthesis. Its molecular structure, featuring bromine and fluorine substituents on a benzonitrile core, makes it a critical intermediate for constructing complex molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring halogenated aromatic motifs for bioactivity or metabolic stability.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, where the bromo and fluoro groups can enhance binding affinity and environmental persistence.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of organic electronic materials, liquid crystals, and advanced polymers where specific halogen interactions are required.
• Chemical Biology Probes: Useful for synthesizing molecular probes and tags for studying biological systems and protein interactions.
• Custom Synthesis and Scale-up: A fundamental building block for contract research organizations (CROs) and custom synthesis manufacturers serving diverse R&D pipelines.

Basic Information

Product Name	2-Bromo-4-Fluorobenzonitrile
CAS No.	36282-26-5
Molecular Formula	C7H3BrFN
Molecular Weight	200.01 g/mol
Synonyms	4-Fluoro-2-bromobenzonitrile; 2-Bromo-4-fluorobenzene carbonitrile; 2-Bromo-4-fluorophenyl cyanide; Benzonitrile, 2-bromo-4-fluoro-; (2-Bromo-4-fluorophenyl)carbonitrile; 36282-26-5; 4-Fluoro-2-bromobenznitrile
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-Fluorobenzonitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with the standards required for pharmaceutical and agrochemical intermediate applications, ensuring reliable integration into your sensitive synthesis processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.