Description

Propranolol Glycol is a key pharmaceutical intermediate, specifically the glycol ester derivative of the widely used β-blocker, propranolol. This compound is valued for its role in the synthesis and development of advanced drug formulations, offering enhanced solubility and bioavailability characteristics. It is primarily required by pharmaceutical manufacturers and research institutions engaged in cardiovascular drug development, process chemistry, and the creation of novel propranolol-based therapeutic agents.

Application

• Pharmaceutical Intermediate: Primary use in the synthesis of propranolol and its related drug substances.
• Drug Formulation Research: Employed in developing modified-release or solubility-enhanced formulations of propranolol.
• Process Chemistry: Serves as a critical building block in multi-step organic synthesis for active pharmaceutical ingredients (APIs).
• Analytical Reference Standard: Used as a certified reference material (CRM) for quality control and method validation in analytical laboratories.
• Metabolite Studies: Utilized in pharmacological and pharmacokinetic research to study drug metabolism pathways.
• Chemical Synthesis: Acts as a precursor for the preparation of other specialty esters and derivatives for research purposes.

Basic Information

Product Name	Propranolol Glycol
CAS No.	36112-95-5
Molecular Formula	C16H25NO3
Molecular Weight	279.38 g/mol
Synonyms	1,2-Propanediol, 1-[(1-methylethyl)amino]-3-(1-naphthalenyloxy)-, (2R)-; (R)-1-((1-Methylethyl)amino)-3-(naphthalen-1-yloxy)propan-2-ol; Propranolol Glycol Ester; 1,2-Propanediol, 1-(isopropylamino)-3-(1-naphthyloxy)-, (R)-; Glycol ester of Propranolol; Propranolol 1,2-Glycol; Propranolol PG Ester
EINECS	Contact for details

Quality Control

Our Propranolol Glycol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, assay, and impurity profiling, to ensure it meets the high-purity standards required for pharmaceutical applications. Certificates of Analysis (COA) detailing specifications and test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.