Description

20-Dihydrocorticosterone is a key intermediate in the synthesis of various steroid hormones and a metabolite of corticosterone. This compound is of significant value in pharmaceutical research and development, particularly for studying glucocorticoid metabolism and related endocrine pathways. It is primarily utilized by research institutions, pharmaceutical manufacturers, and biotechnology companies engaged in steroid chemistry, metabolic studies, and the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of more complex corticosteroid analogs and other steroid-based active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard and reagent in metabolic pathway studies, enzyme inhibition assays, and glucocorticoid receptor research.
• Endocrinology Studies: Employed to investigate the biosynthesis, regulation, and physiological effects of adrenal cortex hormones.
• Analytical Standard: Serves as a high-purity certified reference material (CRM) for qualitative and quantitative analysis in laboratories (e.g., HPLC, LC-MS).
• Preclinical Development: Utilized in the early-stage development and screening of new drug candidates targeting steroid hormone pathways.

Basic Information

Product Name	20-Dihydrocorticosterone
CAS No.	35531-74-9
Molecular Formula	C21H32O4
Molecular Weight	348.48 g/mol
Synonyms	20α-Dihydrocorticosterone; 11β,21-Dihydroxypregn-4-ene-3,20-dione; 20α-Hydroxycorticosterone; 5β-Pregnane-3,11,20-trione, 21-hydroxy-; 20-DHC; 20α-DHC; 11β,21-Dihydroxy-4-pregnene-3,20-dione
EINECS	Contact for details

Quality Control

Our 20-Dihydrocorticosterone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and pharmaceutical applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.