Description

Bunitrolol is a selective β-adrenergic receptor antagonist (β-blocker) with the CAS registry number 34915-68-9. This compound is a key pharmaceutical intermediate and research chemical of significant interest for its cardiovascular activity. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Critical building block in the synthesis of advanced β-blocker APIs for cardiovascular research and development.
• Biochemical Research: Used as a reference standard and tool compound in pharmacological studies to investigate β-adrenergic receptor mechanisms.
• Preclinical Development: Serves as a starting material or intermediate in the development of new therapeutic candidates targeting hypertension and angina.
• Analytical Standard: Employed in quality control laboratories for method development, validation, and as a certified reference material (CRM).
• Academic Research: Utilized in university and institutional labs for studying structure-activity relationships (SAR) of adrenergic agents.

Basic Information

Product Name	Bunitrolol
CAS No.	34915-68-9
Molecular Formula	C17H20N2O3
Molecular Weight	300.35 g/mol
Synonyms	Bunitrolol; 2-[3-[(1,1-Dimethylethyl)amino]-2-hydroxypropoxy]benzonitrile; (±)-Bunitrolol; Bunitrololum; Koe 1366; DL-Bunitrolol; Bunitrolol Hydrochloride (salt form)
EINECS	Contact for details

Quality Control

Our Bunitrolol is produced under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0% Any single unknown impurity ≤0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.