Description

2-Fluoro-4-Nitrobenzonitrile is a versatile aromatic nitrile building block characterized by its electron-withdrawing nitro and fluorine substituents. This compound is critical for synthesizing complex molecules, particularly in the development of advanced agrochemicals and active pharmaceutical ingredients (APIs). It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing heterocyclic compounds and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and pesticides, leveraging its structural motif for enhanced biological activity.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of specialty polymers and liquid crystals.
• Organic Synthesis Building Block: Employed in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce fluorinated aromatic systems.
• Dye and Pigment Intermediate: Utilized in the production of advanced colorants and fluorescent markers due to its nitrobenzonitrile core.

Basic Information

Product Name	2-Fluoro-4-Nitrobenzonitrile
CAS No.	34667-88-4
Molecular Formula	C7H3FN2O2
Molecular Weight	166.11 g/mol
Synonyms	4-Nitro-2-fluorobenzonitrile; 2-Fluoro-4-nitrobenzenecarbonitrile; Benzonitrile, 2-fluoro-4-nitro-; 2-Fluoro-4-cyanointrobenzene; 2-Fluoro-4-nitro-phenyl cyanide; 34667-88-4; FC6H3(4-NO2)CN
EINECS	Contact for details

Quality Control

Our 2-Fluoro-4-Nitrobenzonitrile is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We adhere to cGMP guidelines where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	108 - 112 °C
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.