Description

2-Methoxy-5-(Trifluoromethyl)Benzonitrile is a versatile aromatic nitrile derivative distinguished by its methoxy and trifluoromethyl substituents. This compound is a high-value pharmaceutical intermediate and agrochemical building block, prized for its ability to impart metabolic stability and lipophilicity to target molecules. It is essential for R&D and production in the pharmaceutical, crop protection, and advanced material science sectors.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Serves as a critical precursor for developing novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the trifluoromethyl group.
• Liquid Crystal & OLED Materials: Used in the research and production of advanced electronic display materials and organic light-emitting diodes (OLEDs).
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Sonogashira) and cyano group transformations to create complex molecular architectures.
• Chemical Research & Development: A valuable reagent for medicinal chemistry and material science research in academic and industrial laboratories.
• Dye & Pigment Intermediate: Utilized in the synthesis of specialized dyes and pigments requiring specific electronic properties.

Basic Information

Product Name	2-Methoxy-5-(Trifluoromethyl)Benzonitrile
CAS No.	34636-92-5
Molecular Formula	C9H6F3NO
Molecular Weight	201.15 g/mol
Synonyms	5-(Trifluoromethyl)-2-methoxybenzonitrile; 2-Methoxy-α,α,α-trifluoro-p-tolunitrile; 2-Methoxy-α,α,α-trifluoro-4-methylbenzonitrile; 2-Methoxy-5-(trifluoromethyl)phenyl cyanide; 4-Cyano-3-methoxybenzotrifluoride; 5-(Trifluoromethyl)-o-anisonitrile; Benzonitrile, 2-methoxy-5-(trifluoromethyl)-; p-(Trifluoromethyl)-o-methoxybenzonitrile
EINECS	Contact for details

Quality Control

Our 2-Methoxy-5-(Trifluoromethyl)Benzonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical and agrochemical applications. Certificates of Analysis (COA) detailing batch-specific results are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.