Description

Clocortolone Pivalate is a synthetic corticosteroid ester specifically designed for topical application. This compound is valued for its potent anti-inflammatory and antipruritic properties, making it a critical active pharmaceutical ingredient (API) in dermatological formulations. It is primarily utilized by pharmaceutical manufacturers and R&D institutions focused on developing treatments for various skin conditions, including eczema, psoriasis, and dermatitis.

Application

• Topical Corticosteroid Formulations: As the core API in creams, ointments, and lotions for treating inflammatory skin disorders.
• Dermatological R&D: Serves as a key reference standard and intermediate in the research and development of new topical anti-inflammatory agents.
• Pharmaceutical Intermediates: Used in the synthesis of more complex steroid-based drug molecules.
• Veterinary Medicine: Incorporated into topical preparations for managing skin inflammation in animals.
• Compounding Pharmacy: Employed by specialized pharmacies to prepare customized topical medications for specific patient needs.

Basic Information

Item	Details
Product Name	Clocortolone Pivalate
CAS No.	34097-16-0
Molecular Formula	C₂₇H₃₅ClO₅
Molecular Weight	475.02 g/mol
Synonyms	Clocortolone Trimethylacetate; Clocortolone Pivalate; Clocortolone 21-Pivalate; 9-Chloro-6α-fluoro-11β,21-dihydroxy-16α-methylpregna-1,4-diene-3,20-dione 21-pivalate; 9-Chloro-6α-fluoro-11β,21-dihydroxy-16α-methyl-1,4-pregnadiene-3,20-dione 21-pivalate; 9-Chloro-6α-fluoro-16α-methylprednisolone 21-pivalate; Cloderm (brand name); SQ-18566
EINECS	Contact for details

Quality Control

Our Clocortolone Pivalate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for assay and purity, identification by IR spectroscopy, and control of related substances and residual solvents, to ensure it meets high-grade pharmaceutical standards. A Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to standard
Assay (HPLC)	98.0% - 102.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.