Description

10-(4-Amino-5-Hydroxy-6-Methyl-Oxan-2-Yl)Oxy-6,8,11-Trihydroxy-8-(n-Hydroxy-C-Methyl-Carbonimidoyl)-1-Methoxy-9,10-Dihydro-7H-Tetracene-5,12-Dione is a complex, high-purity anthracycline derivative with significant biological activity. This compound is valued for its role as a critical intermediate and reference standard in advanced pharmaceutical research and development. It is primarily required by R&D laboratories and manufacturers in the pharmaceutical and biotechnology sectors for the synthesis and quality control of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel anthracycline-based chemotherapeutic agents and antibiotics.
• Research & Development: Used as a reference standard and active pharmaceutical ingredient (API) precursor in pharmacological and biochemical research studies.
• Analytical Standard: Serves as a high-purity calibration standard for HPLC, LC-MS, and other analytical methods in quality control laboratories.
• Biochemical Studies: Employed in studies investigating DNA intercalation mechanisms, topoisomerase inhibition, and structure-activity relationships (SAR).
• Academic Research: Utilized in university and institutional labs for chemical synthesis projects and the development of new synthetic methodologies.

Basic Information

Product Name	10-(4-Amino-5-Hydroxy-6-Methyl-Oxan-2-Yl)Oxy-6,8,11-Trihydroxy-8-(n-Hydroxy-C-Methyl-Carbonimidoyl)-1-Methoxy-9,10-Dihydro-7H-Tetracene-5,12-Dione
CAS No.	33644-59-6
Molecular Formula	C27H30N2O12
Molecular Weight	574.54 g/mol
Synonyms	4'-Epidoxorubicin; 4'-Epidoxorubicinone; 4'-Epidoxorubicinol; 4'-Epidoxorubicinolone; 4'-Epidoxorubicinolone aglycone; 4'-Epidoxorubicinolone aglycone derivative; 4'-Epidoxorubicinolone aglycone methyl ether; 4'-Epidoxorubicinolone aglycone methyl ether derivative
EINECS	Contact for details

Quality Control

Our 10-(4-Amino-5-Hydroxy-6-Methyl-Oxan-2-Yl)Oxy-6,8,11-Trihydroxy-8-(n-Hydroxy-C-Methyl-Carbonimidoyl)-1-Methoxy-9,10-Dihydro-7H-Tetracene-5,12-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC purity analysis and structural confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	Orange to red powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.