Description

Diflorasone Diacetate is a synthetic corticosteroid ester with potent anti-inflammatory and antipruritic properties. This high-purity active pharmaceutical ingredient (API) is critical for formulating effective topical dermatological treatments. It is primarily required by pharmaceutical manufacturers and R&D institutions specializing in dermatology and steroid chemistry.

Application

• Topical Corticosteroid Formulations: Primary active ingredient in creams, ointments, and lotions for treating inflammatory skin conditions such as psoriasis, eczema, and contact dermatitis.
• Veterinary Dermatology: Used in medicated preparations for managing inflammatory skin disorders in animals.
• Pharmaceutical Research & Development: Serves as a key reference standard and intermediate in the synthesis and development of new steroid-based therapeutics.
• Clinical Compound Libraries: Supplied to research organizations for high-throughput screening and biological activity studies.
• Generic Drug Manufacturing: Essential for producing generic versions of branded topical corticosteroid products containing diflorasone diacetate.

Basic Information

Product Name	Diflorasone Diacetate
CAS No.	33564-31-7
Molecular Formula	C₂₆H₃₂F₂O₇
Molecular Weight	494.53 g/mol
Synonyms	6α,9-Difluoro-11β,17,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione 17,21-diacetate; 6α,9-Difluoro-11β,17,21-trihydroxy-16β-methyl-1,4-pregnadiene-3,20-dione 17,21-diacetate; Diflorasone 17,21-Diacetate; NSC-114649; Flucort; Flucort-N; Diflucortolone Valerate Impurity C (Diacetate)
EINECS	Contact for details

Quality Control

Our Diflorasone Diacetate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. A Certificate of Analysis (COA) detailing identity, purity, and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.