Description

Benzonitrile, 4-[5-(Trifluoromethyl)-1H-Imidazol-2-Yl]- is a high-value, heterocyclic aromatic nitrile building block featuring a trifluoromethyl-substituted imidazole ring. This compound is critical for advanced organic synthesis, offering a unique combination of electronic and steric properties that enable the development of novel active molecules. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for creating new active ingredients, as well as by fine chemical manufacturers for custom synthesis projects.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitor and anti-inflammatory research.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the bioactivity of the imidazole and trifluoromethyl motifs.
• Material Science Research: Serves as a precursor for functionalized ligands and monomers in the development of specialty polymers and advanced materials.
• Chemical Biology & Proteomics: Employed as a building block for activity-based probes and molecular tags due to its reactive nitrile group.
• Custom Synthesis & Contract Manufacturing: Supplied to fine chemical companies for bespoke synthesis projects requiring this specific heterocyclic architecture.

Basic Information

Product Name	Benzonitrile, 4-[5-(Trifluoromethyl)-1H-Imidazol-2-Yl]-
CAS No.	33469-11-3
Molecular Formula	C11H6F3N3
Molecular Weight	237.18 g/mol
Synonyms	4-(5-(Trifluoromethyl)-1H-imidazol-2-yl)benzonitrile; 2-(4-Cyanophenyl)-5-(trifluoromethyl)-1H-imidazole; 5-(Trifluoromethyl)-2-(4-cyanophenyl)imidazole; 2-(4-Cyanophenyl)-5-trifluoromethylimidazole; 4-(5-Trifluoromethyl-1H-imidazol-2-yl)benzonitrile; 33469-11-3; 4-(5-(Trifluoromethyl)-1H-imidazol-2-yl)benzonitrile
EINECS	Contact for details

Quality Control

Our production of Benzonitrile, 4-[5-(Trifluoromethyl)-1H-Imidazol-2-Yl]- adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling, to meet the exacting standards required for research and synthesis applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and conformance to agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure containers are sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.