Description

1-Fluoro-2-(Dichloromethyl)-3-Chloro-4-Nitrobenzene is a specialized halogenated nitrobenzene derivative, serving as a versatile and critical building block in advanced organic synthesis. Its unique substitution pattern makes it a valuable precursor for the development of complex molecules, particularly in the agrochemical and pharmaceutical sectors. This high-purity intermediate is essential for research and manufacturing chemists requiring precise, multi-functional aromatic compounds for constructing active ingredients and novel materials.

Application

• Agrochemical Intermediate: A key synthon for the synthesis of advanced herbicides, fungicides, and pesticides, leveraging its halogen and nitro functional groups for bioactivity.
• Pharmaceutical Building Block: Used in the research and development of active pharmaceutical ingredients (APIs), especially those requiring fluorinated and chlorinated aromatic cores.
• Dye and Pigment Synthesis: Serves as a precursor in the manufacture of specialized dyes and pigments, where the nitro group is a crucial intermediate for azo and other chromophore formations.
• Material Science Research: Employed in the development of advanced polymers, liquid crystals, and electronic materials that incorporate halogenated aromatic units.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) due to the presence of reactive halogen atoms.
• Nucleophilic Aromatic Substitution: The activated nitro and halogen groups make it an excellent candidate for nucleophilic substitution reactions to create diverse chemical libraries.

Basic Information

Product Name	1-Fluoro-2-(Dichloromethyl)-3-Chloro-4-Nitrobenzene
CAS No.	33429-69-5
Molecular Formula	C7H3Cl3FNO2
Molecular Weight	258.46 g/mol
Synonyms	2-(Dichloromethyl)-1-fluoro-3-chloro-4-nitrobenzene; 3-Chloro-2-(dichloromethyl)-1-fluoro-4-nitrobenzene; Benzene, 1-fluoro-2-(dichloromethyl)-3-chloro-4-nitro-; 1-Fluoro-3-chloro-2-(dichloromethyl)-4-nitrobenzene; 4-Nitro-1-fluoro-2-(dichloromethyl)-3-chlorobenzene
EINECS	Contact for details

Quality Control

Our production of 1-Fluoro-2-(Dichloromethyl)-3-Chloro-4-Nitrobenzene adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, GC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be opaque or stored in darkness.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.