Description

1-Chloro-2-(Dichloromethyl)-3-Fluoro-4-Nitrobenzene is a high-purity, multi-halogenated aromatic compound serving as a critical building block in advanced organic synthesis. Its unique structure, featuring chloro, dichloromethyl, fluoro, and nitro substituents, makes it an invaluable intermediate for creating complex molecules with tailored properties. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key synthon for the research and development of new drug candidates, particularly in fluorinated and nitro-aromatic series.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where halogenated nitrobenzenes impart specific biological activity.
• Material Science Research: Serves as a precursor for synthesizing specialty polymers, liquid crystals, and organic electronic materials.
• Dye and Pigment Intermediate: Employed in the development of complex, high-performance colorants and photographic chemicals.
• Cross-Coupling Reactions: A valuable substrate for palladium-catalyzed reactions (e.g., Suzuki, Stille) to create diverse biaryl structures.
• Nucleophilic Aromatic Substitution: The activated nitro and halogen groups make it a reactive partner for designing novel aromatic compounds.

Basic Information

Product Name	1-Chloro-2-(Dichloromethyl)-3-Fluoro-4-Nitrobenzene
CAS No.	33429-68-4
Molecular Formula	C7H3Cl3FNO2
Molecular Weight	258.46 g/mol
Synonyms	2-(Dichloromethyl)-1-chloro-3-fluoro-4-nitrobenzene; 3-Fluoro-4-nitrobenzotrichloride (related); 1-Chloro-2-(dichloromethyl)-3-fluoro-4-nitro-benzene; Benzene, 1-chloro-2-(dichloromethyl)-3-fluoro-4-nitro-; 4-Nitro-1-chloro-2-(dichloromethyl)-3-fluorobenzene
EINECS	Contact for details

Quality Control

Our 1-Chloro-2-(Dichloromethyl)-3-Fluoro-4-Nitrobenzene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, GC for residual solvents, and NMR/IR for structural confirmation to ensure consistent identity and high purity. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.