Description

3-Buten-2-One, 4-(Dimethylamino)-4-Fluoro-, (Z)- (8Ci,9Ci) is a specialized fluorinated enaminone derivative with a defined stereochemistry. This compound serves as a versatile and high-value building block in advanced organic synthesis, particularly for constructing complex molecular architectures. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of fluorinated drug candidates, including potential kinase inhibitors and central nervous system (CNS) active compounds.
• Agrochemical Research: Used in creating novel fluorinated pesticides and herbicides, where the fluorine atom can enhance biological activity and metabolic stability.
• Material Science: Serves as a precursor for advanced organic materials, such as liquid crystals or organic semiconductors, leveraging its conjugated system and functional groups.
• Academic & Contract Research: Employed in methodological studies and as a building block for complex natural product analogs and chemical libraries.
• Fluorine Chemistry: A valuable substrate for studying and developing new fluorination reactions and catalytic processes.

Basic Information

Item	Detail
Product Name	3-Buten-2-One, 4-(Dimethylamino)-4-Fluoro-, (Z)- (8Ci,9Ci)
CAS No.	32643-69-9
Molecular Formula	C6H10FNO
Molecular Weight	131.15 g/mol
Synonyms	(Z)-4-(Dimethylamino)-4-fluoro-3-buten-2-one; 4-(Dimethylamino)-4-fluoro-3-buten-2-one, (Z)-; 4-Fluoro-4-(dimethylamino)-3-buten-2-one; (Z)-1-(Dimethylamino)-1-fluoro-1,3-butadien-2-one; Fluorinated enaminone; 4-Dimethylamino-4-fluoro-but-3-en-2-one
EINECS	Contact for details

Quality Control

Our production of 3-Buten-2-One, 4-(Dimethylamino)-4-Fluoro-, (Z)- adheres to stringent quality protocols. Each batch is characterized and tested to ensure identity, purity, and consistency, meeting the exacting standards required for research and process development. A comprehensive Certificate of Analysis (COA) detailing purity (typically by HPLC or GC), identity confirmation (by IR, NMR), and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. Allow the container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 95% (Typical 97-99%)
Water Content (KF)	≤ 0.5%
Isomeric Purity (Z-isomer)	≥ 98%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.