Description

Pyridine Hydrofluoride is a versatile fluorinating agent and a source of fluoride ion, formed by the complexation of pyridine with hydrogen fluoride. This compound is valued for its ability to facilitate challenging fluorination reactions under relatively mild conditions, offering a safer and more controllable alternative to anhydrous hydrogen fluoride. It is primarily sought after by research laboratories and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for synthesizing fluorinated intermediates and active ingredients.

Application

• Pharmaceutical Synthesis: A key reagent for introducing fluorine atoms into drug molecules to enhance metabolic stability, bioavailability, and binding affinity.
• Agrochemical Production: Used in the manufacture of fluorinated pesticides and herbicides, where the fluorine atom can improve efficacy and environmental persistence.
• Organic Fluorination Reactions: Employed as a nucleophilic fluorinating agent in the synthesis of alkyl fluorides, aryl fluorides, and other fluoroorganic compounds.
• Catalyst and Ligand Precursor: Serves as a starting material for generating metal-fluoride complexes used in catalysis.
• Laboratory Reagent: Utilized in research and development for method development and small-scale synthesis of fluorinated target molecules.
• Surface Treatment & Etching: Applied in specialized material science processes for surface modification or etching of silicon-based materials.

Basic Information

Product Name	Pyridine Hydrofluoride
CAS No.	32001-55-1
Molecular Formula	C5H6FN
Molecular Weight	99.11 g/mol
Synonyms	Pyridinium Fluoride; Pyridine Hydrogen Fluoride; Pyridine-HF Complex; Fluoropyridinium; Pyridine Fluorohydrate; Hydrogen Fluoride Pyridine Complex; Pyridine, hydrofluoride
EINECS	Contact for details

Quality Control

Our Pyridine Hydrofluoride is produced and tested under stringent quality management protocols. Each batch is analyzed to ensure high chemical purity and consistency, with specifications tailored to meet the demands of fine chemical synthesis. A comprehensive Certificate of Analysis (COA) detailing assay, impurity profile, and physical characteristics is provided with every shipment to guarantee traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Due to its hygroscopic and highly volatile nature, containers must be kept tightly sealed and away from moisture. Handle and store in accordance with all applicable local, national, and international regulations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms
Assay (Pyridine Hydrofluoride)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Pyridine Content	Contact for details
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.