Description

11β,17,21-Trihydroxy-20-Oxo-5α-Pregnan-3α-Yl β is a high-purity steroid derivative and a key intermediate in advanced pharmaceutical synthesis. This compound is critical for research and development in the production of specialized corticosteroids and other therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in steroid chemistry and drug discovery.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of potent corticosteroid APIs (Active Pharmaceutical Ingredients).
• Research & Development: Used in medicinal chemistry for the development of novel anti-inflammatory and immunosuppressive agents.
• Reference Standard: Serves as a certified reference material (CRM) for analytical method development and quality control in pharmaceutical labs.
• Biochemical Research: Employed in studies investigating steroid hormone metabolism, receptor binding, and enzymatic pathways.
• Fine Chemical Synthesis: A versatile precursor for creating custom steroid analogs with modified biological activity.

Basic Information

Item	Details
Product Name	11β,17,21-Trihydroxy-20-Oxo-5α-Pregnan-3α-Yl β
CAS No.	30954-21-3
Molecular Formula	C21H32O5
Molecular Weight	364.48 g/mol
Synonyms	11β,17α,21-Trihydroxy-5α-pregnane-3α,20-dione; 5α-Pregnan-3α-ol-11β,17α,21-triol-20-one; 11β,17α,21-Trihydroxypregn-4-ene-3,20-dione 3α-isomer; Tetrahydrocortisol (3α,5α); 3α,5α-Tetrahydrocortisol; 5α-Tetrahydrocortisol; Urocortisol; (3α,5α,11β)-11,17,21-Trihydroxypregnane-20-one
EINECS	Contact for details

Quality Control

Our 11β,17,21-Trihydroxy-20-Oxo-5α-Pregnan-3α-Yl β is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets exacting standards for pharmaceutical research. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Specific Rotation	Contact for details
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.