Description

(1R,2S,4As,12Ar)-3-Acetyl-1,2,6,7-Tetrahydroxy-4A-[(2S,5S,6S)-5-Hydroxy-5-(2-Hydroxyacetyl)-6-Methyl-Oxan-2-Yl]Oxy-1,2,12,12A-Tetrahydrotetracen-5-One is a complex, high-purity tetracyclic compound belonging to the anthracycline/tetracene derivative family. This molecule is of significant interest for its potential as a key synthetic intermediate or a pharmacologically active scaffold in advanced research and development. It is primarily sought after by pharmaceutical R&D laboratories, biotechnology firms, and academic institutions engaged in the synthesis of novel therapeutic agents, particularly in oncology and antibiotic research.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the multi-step synthesis of novel anthracycline analogs and other complex bioactive molecules.
• Research & Development: Used as a reference standard or starting material in medicinal chemistry programs targeting DNA-interactive agents and topoisomerase inhibitors.
• Biochemical Research: Employed in studies investigating structure-activity relationships (SAR) of tetracyclic compounds and their mechanisms of biological action.
• Academic Synthesis: A valuable compound for advanced organic chemistry research and methodology development due to its intricate stereochemistry and functional groups.
• Pre-clinical Studies: Potential use in the development and evaluation of new chemotherapeutic candidates in pre-clinical models.

Basic Information

Product Name	(1R,2S,4As,12Ar)-3-Acetyl-1,2,6,7-Tetrahydroxy-4A-[(2S,5S,6S)-5-Hydroxy-5-(2-Hydroxyacetyl)-6-Methyl-Oxan-2-Yl]Oxy-1,2,12,12A-Tetrahydrotetracen-5-One
CAS No.	30361-37-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	3-Acetyl-1,2,6,7-tetrahydroxy-4a-[(5-hydroxy-5-(2-hydroxyacetyl)-6-methyloxan-2-yl)oxy]-1,2,12,12a-tetrahydrotetracene-5-one; 4a-[(5-Hydroxy-5-(2-hydroxyacetyl)-6-methyl-2-oxanyl)oxy]-3-acetyl-1,2,6,7-tetrahydroxy-1,2,12,12a-tetrahydrotetracen-5-one; Tetrahydrotetracenone derivative; Anthracycline derivative intermediate; Complex tetracyclic ketone; CAS 30361-37-6
EINECS	Contact for details

Quality Control

Our (1R,2S,4As,12Ar)-3-Acetyl-1,2,6,7-Tetrahydroxy-4A-[(2S,5S,6S)-5-Hydroxy-5-(2-Hydroxyacetyl)-6-Methyl-Oxan-2-Yl]Oxy-1,2,12,12A-Tetrahydrotetracen-5-One is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS), to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.