Description

Xibenolol CAS NO 30187-90-7 is a high-purity pharmaceutical intermediate and research chemical of significant importance in modern medicinal chemistry. Its primary value lies in its role as a key building block for the synthesis of advanced β-adrenergic blocking agents (β-blockers). This compound is essential for pharmaceutical R&D laboratories, contract manufacturing organizations (CMOs), and fine chemical suppliers serving the global life sciences sector.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel β-blocker active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a scaffold or starting material for structure-activity relationship (SAR) studies and the development of new cardiovascular drugs.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Process Development: Employed in the optimization and scale-up of synthetic routes within pilot plants and commercial manufacturing.
• Biochemical Research: Utilized in studies investigating adrenergic receptor binding and function.

Basic Information

Product Name	Xibenolol
CAS No.	30187-90-7
Molecular Formula	C15H24N2O3
Molecular Weight	280.36 g/mol
Synonyms	Xibenolol; (±)-Xibenolol; 1-(tert-Butylamino)-3-[(2-cyclohexylphenoxy)methyl]propan-2-ol; 2-Propanol, 1-[(1,1-dimethylethyl)amino]-3-[(2-cyclohexylphenoxy)methyl]-; (±)-1-(tert-Butylamino)-3-(2-cyclohexylphenoxy)-2-propanol; BRN 2932415; CHEMBL3183299; DTXSID4042230
EINECS	Contact for details

Quality Control

Our Xibenolol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and residual solvent analysis. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.