Description

Pregna-1,4-Diene-3,20-Dione, 9-Fluoro-11,17-Dihydroxy-16-Methyl-21-[(3-Sulfobenzoyl)Oxy]-, Monosodium Salt, (11Beta,16Alpha)- is a high-purity synthetic corticosteroid derivative, specifically a water-soluble prodrug form. This compound is critical for pharmaceutical research and development, offering a key intermediate for advanced therapeutic formulations. It is primarily required by R&D laboratories and manufacturers in the pharmaceutical industry focusing on anti-inflammatory and immunosuppressive agents.

Application

• Pharmaceutical Intermediate: Key starting material or intermediate in the synthesis of potent topical and systemic corticosteroid APIs.
• Research & Development: Used in biochemical and pharmacological research to study glucocorticoid receptor activity and metabolic pathways.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Prodrug Development: Utilized in the design and evaluation of water-soluble prodrugs to enhance drug delivery and bioavailability.
• Formulation Studies: Employed in pre-formulation and stability studies for injectable or other dosage forms requiring soluble steroid components.

Basic Information

Item	Detail
Product Name	Pregna-1,4-Diene-3,20-Dione, 9-Fluoro-11,17-Dihydroxy-16-Methyl-21-[(3-Sulfobenzoyl)Oxy]-, Monosodium Salt, (11Beta,16Alpha)-
CAS No.	3936-02-5
Molecular Formula	C29H32FNaO9S
Molecular Weight	598.62 g/mol
Synonyms	Betamethasone Sodium Phosphate Related Compound C; 21-(3-Sulfobenzoyl)betamethasone Sodium Salt; 9α-Fluoro-11β,17α,21-trihydroxy-16α-methylpregna-1,4-diene-3,20-dione 21-(3-sulfobenzoate) Sodium Salt; Betamethasone 21-(3-Sulfobenzoate) Sodium Salt; CL-34699; Sodium 9-fluoro-11β,17-dihydroxy-16α-methyl-3,20-dioxopregna-1,4-dien-21-yl 3-sulfobenzoate
EINECS	Contact for details

Quality Control

Our Pregna-1,4-Diene-3,20-Dione, 9-Fluoro-11,17-Dihydroxy-16-Methyl-21-[(3-Sulfobenzoyl)Oxy]-, Monosodium Salt, (11Beta,16Alpha)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting standards for pharmaceutical research. Certificates of Analysis (COA) with full traceability are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.