Description

6β-Methyl Fluorometholone is a synthetic corticosteroid derivative, specifically a fluorinated glucocorticoid. This compound is valued for its potent anti-inflammatory and immunosuppressive properties, making it a critical intermediate in advanced pharmaceutical synthesis. It is primarily required by research institutions and pharmaceutical manufacturers developing topical and ophthalmic corticosteroid treatments.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potent topical corticosteroid APIs.
• Ophthalmic Drug Development: Research and production of anti-inflammatory eye drops and ointments.
• Dermatological Formulations: Used in the development of creams and lotions for treating skin inflammation, eczema, and psoriasis.
• Biochemical Research: A reference standard for studying glucocorticoid receptor activity and metabolism.
• Veterinary Medicine: Component in anti-inflammatory preparations for animal healthcare.

Basic Information

Product Name	6β-Methyl Fluorometholone
CAS No.	3918-13-6
Molecular Formula	C₂₃H₃₁FO₅
Molecular Weight	406.49 g/mol
Synonyms	6β-Methylfluorometholone; Fluorometholone 6β-methyl derivative; 9α-Fluoro-11β,17α-dihydroxy-6β-methylpregna-1,4-diene-3,20-dione; (6β,11β,17α)-9-Fluoro-11,17-dihydroxy-6-methylpregna-1,4-diene-3,20-dione; 6-Methylfluorometholone
EINECS	Contact for details

Quality Control

Our 6β-Methyl Fluorometholone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy. Certificates of Analysis (COA) detailing purity, related substances, and residual solvents are provided to ensure compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.