Description

Triamcinolone Acetonide 21-Acetate is a synthetic corticosteroid derivative, specifically an esterified form of triamcinolone acetonide, with the CAS registry number 3870-07-3. This compound is valued for its potent anti-inflammatory and immunosuppressive properties, making it a critical intermediate in advanced pharmaceutical synthesis. It is primarily required by manufacturers in the pharmaceutical industry engaged in the research, development, and production of topical and injectable corticosteroid medications.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potent topical corticosteroids for treating skin conditions like eczema, psoriasis, and dermatitis.
• Active Pharmaceutical Ingredient (API) Manufacturing: Used in the production of finished dosage forms, including creams, ointments, and injectable suspensions.
• Research & Development: Serves as a reference standard and a starting material in medicinal chemistry for developing new anti-inflammatory drugs.
• Veterinary Medicine: Employed in the formulation of anti-inflammatory treatments for animals.
• Specialty Chemical Synthesis: Utilized in the preparation of other steroid derivatives for various experimental and therapeutic purposes.

Basic Information

Product Name	Triamcinolone Acetonide 21-Acetate
CAS No.	3870-07-3
Molecular Formula	C₂₆H₃₃FO₇
Molecular Weight	476.54 g/mol
Synonyms	9α-Fluoro-11β,16α,17,21-tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with acetone 21-acetate; Triamcinolone 16,17-acetonide 21-acetate; Fluoxyprednisolone acetonide acetate; Kenalog Acetonide 21-Acetate; Volon A 21-acetate; Aristocort Acetonide 21-Acetate; (11β,16α)-9-Fluoro-11,16,17,21-tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with acetone 21-acetate
EINECS	223-389-8

Quality Control

Our Triamcinolone Acetonide 21-Acetate is manufactured under strict quality management systems. The product undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each batch. We can support compliance with relevant pharmacopeial standards (e.g., USP, EP) upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.