Description

Dexamethasone 23-Dimorpholinophosphinate is a chemically modified derivative of the potent glucocorticoid dexamethasone, designed to enhance its physicochemical properties for specific applications. This compound is valued for its role as a key synthetic intermediate in the development of novel pharmaceutical agents and research tools. It is primarily utilized by research institutions and pharmaceutical companies engaged in advanced steroid chemistry, drug discovery, and the synthesis of targeted prodrugs.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel dexamethasone prodrugs and analogs with modified pharmacokinetic profiles.
• Research & Development: Used in academic and industrial laboratories for studying steroid receptor interactions and developing new anti-inflammatory or immunosuppressive agents.
• Prodrug Synthesis: The dimorpholinophosphinate moiety can be leveraged to create targeted drug delivery systems, improving solubility or tissue specificity.
• Chemical Biology: Serves as a tool compound for probing biological pathways involving glucocorticoid signaling and metabolism.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	Dexamethasone 23-Dimorpholinophosphinate
CAS No.	3864-50-4
Molecular Formula	C33H52N2O7P
Molecular Weight	619.75 g/mol
Synonyms	Dexamethasone 23-(N,N-Dimorpholinophosphinate); 9-Fluoro-11β,17,21-trihydroxy-16α-methylpregna-1,4-diene-3,20-dione 23-(N,N-Dimorpholinophosphinate); Dexamethasone Dimorpholinophosphinate; Dexamethasone Phosphorodiamidate Derivative
EINECS	Contact for details

Quality Control

Our Dexamethasone 23-Dimorpholinophosphinate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets exacting standards for research and development use. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.