Description

Fluperolone is a synthetic corticosteroid with potent anti-inflammatory and immunosuppressive properties. This compound is a critical intermediate in the synthesis of advanced pharmaceutical formulations, valued for its specific glucocorticoid receptor activity. It is primarily utilized by research institutions and pharmaceutical manufacturers developing treatments for inflammatory and autoimmune conditions, as well as in the production of specialized veterinary medicines.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potent topical and systemic corticosteroid APIs.
• Anti-inflammatory Research: Used in preclinical studies to investigate mechanisms of glucocorticoid action and develop new therapeutic agents.
• Veterinary Medicine: Employed in the formulation of anti-inflammatory treatments for companion and livestock animals.
• Reference Standard: Serves as a high-purity analytical standard for quality control and regulatory testing in pharmaceutical labs.
• Biochemical Research: A tool compound for studying steroid hormone pathways and receptor binding assays.

Basic Information

Product Name	Fluperolone
CAS No.	3841-11-0
Molecular Formula	C22H27FO5
Molecular Weight	390.45 g/mol
Synonyms	6α-Fluoro-11β,17α,21-trihydroxypregna-1,4-diene-3,20-dione; 6α-Fluoroprednisolone; Fluprednisolone; NSC-47439; Fluperolone Acetate (related ester); 6-Fluoroprednisolone; 1,4-Pregnadiene-6α-fluoro-11β,17α,21-triol-3,20-dione
EINECS	223-345-5

Quality Control

Our Fluperolone is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, IR for identification, and residual solvent analysis, to ensure it meets exacting standards suitable for pharmaceutical research and development. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which can affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.