Description

1-Fluoro-3-Iodo-5-Nitrobenzene is a high-purity halogenated nitrobenzene derivative, serving as a critical multi-functional building block in advanced organic synthesis. Its unique structure, featuring fluorine, iodine, and nitro substituents, makes it an indispensable precursor for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for applications such as cross-coupling reactions and the synthesis of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs) and drug candidates via Suzuki, Sonogashira, and other palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the halogen and nitro groups facilitate further functionalization.
• Liquid Crystal & OLED Materials: Serves as a building block for creating specialized aromatic cores in electronic materials for displays and lighting applications.
• Organic Ligand Preparation: Employed in the synthesis of complex ligands for catalysis and coordination chemistry.
• Chemical Research & Development: A versatile reagent for exploring new synthetic pathways and creating libraries of compounds for high-throughput screening.
• Dye & Pigment Intermediate: Used in the synthesis of specialized dyes and pigments where halogen and nitro groups modify color and stability properties.

Basic Information

Item	Details
Product Name	1-Fluoro-3-Iodo-5-Nitrobenzene
CAS No.	3819-88-3
Molecular Formula	C6H3FINO2
Molecular Weight	266.99 g/mol
Synonyms	3-Fluoro-5-Iodonitrobenzene; 5-Fluoro-3-Iodonitrobenzene; 1-Fluoro-3-iodo-5-nitro-benzene; 3-Fluoro-5-nitroiodobenzene; 5-Nitro-1-fluoro-3-iodobenzene; 3-Iodo-5-nitrofluorobenzene; Benzene, 1-fluoro-3-iodo-5-nitro-
EINECS	Contact for details

Quality Control

Our 1-Fluoro-3-Iodo-5-Nitrobenzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.