Description

Dexamethasone Hemisuccinate is a water-soluble ester prodrug of the potent glucocorticoid dexamethasone. This chemical modification is crucial for enhancing the bioavailability and formulation flexibility of the active pharmaceutical ingredient. It is primarily utilized in the pharmaceutical industry for the development of injectable and topical formulations, serving researchers and manufacturers focused on anti-inflammatory and immunosuppressive therapies.

Application

• Pharmaceutical Intermediate: Key starting material for synthesizing injectable dexamethasone formulations.
• Steroid Prodrug Development: Used in research and production of prodrugs designed for improved solubility and controlled release.
• Anti-inflammatory Agent: Basis for formulating potent medications to treat severe allergic reactions, dermatological conditions, and autoimmune diseases.
• Veterinary Medicine: Employed in formulations for treating inflammation and shock in animals.
• Ophthalmic Solutions: Intermediate in the production of eye drops for treating inflammatory eye disorders.
• Research & Development: Standard compound for biochemical research, pharmacological studies, and assay development in endocrinology and immunology.

Basic Information

Product Name	Dexamethasone Hemisuccinate
CAS No.	3800-86-0
Molecular Formula	C26H35FO8
Molecular Weight	494.55 g/mol
Synonyms	Dexamethasone 21-Hemisuccinate; Dexamethasone Succinate; 9-Fluoro-11β,17,21-trihydroxy-16α-methylpregna-1,4-diene-3,20-dione 21-hemisuccinate; Dexamethasone 21-(Hydrogen Succinate); SQ-15102; Dexamethasonum hemisuccinatum; Dexamethasone Hydrogen Succinate
EINECS	223-279-8

Quality Control

Our Dexamethasone Hemisuccinate is manufactured under strict quality management systems. Each batch is tested to ensure it meets high-purity standards suitable for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.