Description

1-Nitro-4-(2,2,2-Trifluoroethyl)Benzene is a specialized aromatic nitro compound featuring a trifluoroethyl substituent, making it a valuable fluorinated building block. This compound is significant for its role in advanced organic synthesis, where the nitro group serves as a versatile handle for further functionalization and the trifluoroethyl moiety imparts unique physicochemical properties. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for creating novel molecules with enhanced biological activity or material characteristics.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring fluorinated aromatic structures for improved metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, where the trifluoroethyl group can enhance pesticidal activity and environmental persistence.
• Liquid Crystal & OLED Material Precursor: Acts as a starting material for synthesizing fluorinated components used in liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs) to modify electronic properties and stability.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, reduction to anilines, and nucleophilic aromatic substitution to introduce complex fluorinated aromatic systems into target molecules.
• Dye & Pigment Intermediate: Utilized in the development of specialized dyes and pigments where fluorine substitution alters color fastness and solubility properties.
• Polymer Modification: Incorporated as a monomer or modifier to create fluorinated polymers with specific thermal, chemical, or surface properties.

Basic Information

Item	Details
Product Name	1-Nitro-4-(2,2,2-Trifluoroethyl)Benzene
CAS No.	3764-36-1
Molecular Formula	C8H6F3NO2
Molecular Weight	205.14 g/mol
Synonyms	4-Nitro-α,α,α-trifluoroethylbenzene; p-Nitro(2,2,2-trifluoroethyl)benzene; 2,2,2-Trifluoro-1-(4-nitrophenyl)ethane; 1-(4-Nitrophenyl)-2,2,2-trifluoroethane; 4-(2,2,2-Trifluoroethyl)nitrobenzene; α,α,α-Trifluoro-p-nitrotoluene; (4-Nitrophenyl)trifluoroethane
EINECS	Contact for details

Quality Control

Our 1-Nitro-4-(2,2,2-Trifluoroethyl)Benzene is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chromatographic purity assays and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical properties is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.