Description

Prednisolone 21-3-Sulfobenzoate is a key pharmaceutical intermediate and a chemically modified derivative of the corticosteroid prednisolone. This compound is valued for its role in the synthesis of more complex steroid-based active pharmaceutical ingredients (APIs) and prodrugs, offering enhanced solubility or targeted delivery properties. It is primarily required by pharmaceutical manufacturers and research institutions engaged in the development and production of advanced corticosteroid therapies, anti-inflammatory agents, and specialized ophthalmic preparations.

Application

• Pharmaceutical Intermediate: A critical building block in the multi-step synthesis of novel corticosteroid APIs and prodrugs.
• Anti-inflammatory Drug Research: Used in R&D for developing new steroid derivatives with improved pharmacokinetic profiles.
• Ophthalmic Solution Precursor: Serves as a precursor in formulating specialized ophthalmic corticosteroid treatments.
• Prodrug Synthesis: Utilized to create prodrugs that enhance bioavailability or provide site-specific release of prednisolone.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development and validation.
• Biochemical Research: Used in academic and industrial research to study steroid metabolism and receptor interactions.

Basic Information

Product Name	Prednisolone 21-3-Sulfobenzoate
CAS No.	3694-41-5
Molecular Formula	C28H32O9S
Molecular Weight	544.62 g/mol
Synonyms	Prednisolone 21-(3-Sulfobenzoate); 11β,17α,21-Trihydroxypregna-1,4-diene-3,20-dione 21-(3-Sulfobenzoate); Prednisolone 3'-Sulfobenzoate; 21-(3-Carboxybenzenesulfonyloxy)prednisolone; Benzoic acid, 3-sulfo-, 21-(11β,17α-dihydroxy-3,20-dioxopregna-1,4-dien-21-yl) ester
EINECS	Contact for details

Quality Control

Our Prednisolone 21-3-Sulfobenzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical intermediates. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.