Description

Pregna-1,4-Diene-3,20-Dione, 11,17-Dihydroxy-21-(Sulfooxy)-, Monosodium Salt, (11Beta)- is a high-purity steroid derivative, specifically the monosodium salt of hydrocortisone 21-sulfate. This compound is a critical pharmaceutical intermediate and reference standard used in the research and development of steroidal drugs. It is essential for manufacturers and research institutions in the pharmaceutical, biotechnology, and analytical chemistry sectors who require a reliable and well-characterized raw material for synthesis, method validation, and quality control processes.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of more complex steroidal active pharmaceutical ingredients (APIs) and prodrugs.
• Reference Standard: Used as a certified reference material (CRM) for analytical method development, validation, and calibration in quality control laboratories.
• Biochemical Research: Employed in metabolic studies, enzyme inhibition assays, and research into corticosteroid pathways and receptor binding.
• Impurity Standard: Serves as a known impurity standard for the analysis of related steroid products, ensuring compliance with pharmacopeial purity requirements.
• Veterinary Pharmaceutical Development: Used in the formulation and research of steroidal treatments for animals.

Basic Information

Item	Detail
Product Name	Pregna-1,4-Diene-3,20-Dione, 11,17-Dihydroxy-21-(Sulfooxy)-, Monosodium Salt, (11Beta)-
CAS No.	3664-95-7
Molecular Formula	C21H27NaO8S
Molecular Weight	462.49 g/mol
Synonyms	Hydrocortisone 21-Sulfate Sodium Salt; Cortisol 21-Sulfate Sodium Salt; 11β,17α,21-Trihydroxypregn-4-ene-3,20-dione 21-(Sodium Sulfate); (11β)-11,17-Dihydroxy-21-(sulfooxy)pregna-1,4-diene-3,20-dione monosodium salt; Sodium Hydrocortisone Sulfate; NSC 113935
EINECS	Contact for details

Quality Control

Our Pregna-1,4-Diene-3,20-Dione, 11,17-Dihydroxy-21-(Sulfooxy)-, Monosodium Salt, (11Beta)- is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR, to ensure it meets exacting standards for use as a pharmaceutical intermediate. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.