Description

11Beta,17,21-Trihydroxypregn-4-Ene-3,20-Dione 21-Hexanoate is a synthetic corticosteroid derivative, specifically a 21-hexanoate ester of hydrocortisone. This compound is valued for its role as a key pharmaceutical intermediate in the synthesis of more potent and specialized steroid-based active pharmaceutical ingredients (APIs). It is primarily required by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for the development of anti-inflammatory and immunosuppressive medications.

Application

• Pharmaceutical Intermediate: A critical building block in the multi-step synthesis of advanced corticosteroid APIs.
• Anti-inflammatory Drug Research: Used in R&D for creating novel topical and systemic anti-inflammatory agents.
• Steroid Prodrug Development: Serves as a precursor for prodrugs designed to improve bioavailability and pharmacokinetic profiles.
• Biochemical Research: Employed in studies investigating glucocorticoid receptor interactions and metabolic pathways.
• Reference Standard: Utilized as a high-purity analytical standard for quality control and method validation in pharmaceutical laboratories.

Basic Information

Product Name	11Beta,17,21-Trihydroxypregn-4-Ene-3,20-Dione 21-Hexanoate
CAS No.	3593-96-2
Molecular Formula	C27H40O6
Molecular Weight	460.60 g/mol
Synonyms	Hydrocortisone 21-Hexanoate; 11β,17,21-Trihydroxypregn-4-ene-3,20-dione 21-caproate; Cortisol 21-Hexanoate; 21-Hexanoylhydrocortisone; 11β-Hydroxy-17α,21-dihydroxypregn-4-ene-3,20-dione 21-hexanoate; NSC 10483
EINECS	Contact for details

Quality Control

Our 11Beta,17,21-Trihydroxypregn-4-Ene-3,20-Dione 21-Hexanoate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the stringent requirements for pharmaceutical intermediate use. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.