Description

Propranolol Hydrochloride is a high-purity, non-selective β-adrenergic blocking agent widely recognized for its critical role in cardiovascular and neurological therapeutics. This active pharmaceutical ingredient (API) is essential for formulators requiring a reliable and consistent compound for the production of finished dosage forms. It is primarily utilized by pharmaceutical manufacturers and research institutions in the development and production of medications for hypertension, angina, arrhythmia, migraine prophylaxis, and anxiety management.

Application

• Pharmaceutical API: Primary active ingredient in the manufacture of tablets, capsules, and injectable formulations.
• Cardiovascular Therapeutics: Used in medications for treating hypertension (high blood pressure), angina pectoris, and cardiac arrhythmias.
• Neurological & CNS Applications: Key component in prophylactic treatments for migraine headaches and essential tremor.
• Anxiety Management: Employed in certain situational anxiety treatments due to its peripheral β-blocking effects.
• Clinical Research: Serves as a reference standard and key intermediate in pharmacological studies and new drug development.
• Veterinary Medicine: Applied in veterinary practice for similar cardiovascular indications in animals.

Basic Information

Product Name	Propranolol Hydrochloride
CAS No.	3506-09-0
Molecular Formula	C16H21NO2 • HCl
Molecular Weight	295.80 g/mol
Synonyms	1-(Isopropylamino)-3-(1-naphthyloxy)-2-propanol Hydrochloride; Propranolol HCl; ICI 45520; Inderal; Avlocardyl; Dociton; Angilol; Betachron E-R; Deralin; (RS)-Propranolol Hydrochloride; (±)-Propranolol Hydrochloride
EINECS	222-500-4

Quality Control

Our Propranolol Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets stringent specifications for identity, purity, and potency, aligning with major pharmacopeial standards such as USP, EP, and BP. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with your specified requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under conditions that minimize exposure to atmospheric humidity to maintain stability and efficacy.

Specification

Item	Specification
Appearance	White or almost white crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.5% - 101.0% (on dried basis)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 1.0% Any individual impurity ≤ 0.5%
Optical Rotation	-0.10° to +0.10° (for enantiomeric purity)
Chromatographic Purity (TLC)	Conforms to standard

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.