Description

Pheniramine 4-Aminosalicylate is the 4-aminosalicylic acid salt of the antihistamine pheniramine. This specific salt form is valued for its enhanced stability and solubility profile compared to other pheniramine salts, making it a critical active pharmaceutical ingredient (API) in specialized formulations. It is primarily required by pharmaceutical manufacturers and research institutions developing advanced ophthalmic solutions, nasal sprays, and other topical anti-allergic medications.

Application

• Primary Active Pharmaceutical Ingredient (API) in ophthalmic solutions and eye drops for treating allergic conjunctivitis.
• Key component in nasal spray formulations designed for allergy relief.
• Used in the development of topical creams and gels for skin allergy and itch management.
• Intermediate in the synthesis of more complex pharmaceutical compounds targeting histamine receptors.
• Reference standard in analytical laboratories for quality control and method development.
• Starting material for pharmacological research studying H1-antihistamine effects and delivery systems.

Basic Information

Product Name	Pheniramine 4-Aminosalicylate
CAS No.	3269-83-8
Molecular Formula	C20H21N3O3
Molecular Weight	351.40 g/mol
Synonyms	Pheniramine Aminosalicylate; Pheniramine 4-ASA; N-(4-Aminosalicyloyl)-N',N'-dimethyl-γ-aminopyridine; Avil Aminosalicylate; Prophenpyridamine 4-Aminosalicylate; Feniramina 4-Aminosalicilato; 4-Aminosalicylic Acid Pheniramine Salt
EINECS	Contact for details

Quality Control

Our Pheniramine 4-Aminosalicylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, assay, and impurity profiling by HPLC, to ensure it meets stringent pharmaceutical-grade specifications. Certificates of Analysis (COA) documenting compliance with relevant in-house or client specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.