Description

Antazoline Methanesulfonate is a high-purity pharmaceutical salt form of the antihistamine compound antazoline. This material is a critical active pharmaceutical ingredient (API) and intermediate valued for its precise chemical structure and consistent performance in formulation. It is primarily required by pharmaceutical manufacturers and research institutions engaged in the development and production of ophthalmic solutions, nasal sprays, and other therapeutic agents targeting allergic responses. Our supply ensures the reliability and stringent quality control necessary for advanced medical applications.

Application

• Primary Active Pharmaceutical Ingredient (API) in ophthalmic solutions for allergic conjunctivitis.
• Key intermediate in the synthesis of advanced antihistamine formulations.
• Research and development of novel nasal decongestant and anti-allergy medications.
• Reference standard for analytical method development and quality control laboratories.
• Manufacturing of veterinary pharmaceutical products for allergic conditions.
• Component in stability studies and formulation optimization for drug delivery systems.

Basic Information

Product Name	Antazoline Methanesulfonate
CAS No.	3131-32-6
Molecular Formula	C₁₇H₁₉N₃·CH₄O₃S
Molecular Weight	377.46 g/mol
Synonyms	Antazoline Mesylate; 2-[(N-Benzylanilino)methyl]-2-imidazoline methanesulfonate; Antazoline methanesulphonate; Antistin methanesulfonate; Phenazoline Methanesulfonate; Antazoline Metilsulfate; N-(Benzylphenyl)-N',N'-dimethyl-2-imidazolin-2-ylamine methanesulfonate
EINECS	221-525-8

Quality Control

Our Antazoline Methanesulfonate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. We provide Certificates of Analysis (COA) detailing purity, identity, and impurity profiles, with testing performed in accordance with validated methods. Specifications can be aligned with pharmacopeial standards (such as USP/EP) upon request to support global regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.