Description

1-Ethoxy-4-Nitro-2-(Trifluoromethyl)Benzene is a high-purity, specialized aromatic compound featuring a nitro group and a trifluoromethyl substituent. This unique structure makes it a valuable advanced intermediate for the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is essential for R&D chemists and process development scientists working on novel active ingredients, dyes, and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring fluorinated aromatic systems for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the trifluoromethyl group is a critical pharmacophore.
• Dye and Pigment Manufacturing: Serves as a precursor for the development of specialized dyes and pigments, leveraging the nitro and ethoxy groups for color and property tuning.
• Organic Electronics Research: Investigated as a potential component or dopant in the development of organic light-emitting diodes (OLEDs) and semiconductors due to its electron-withdrawing characteristics.
• Liquid Crystal and Polymer Additive: Can be utilized in the synthesis of monomers or additives for high-performance polymers and liquid crystal displays (LCDs).
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) for constructing complex biaryl structures in medicinal chemistry.

Basic Information

Product Name	1-Ethoxy-4-Nitro-2-(Trifluoromethyl)Benzene
CAS No.	3094-08-4
Molecular Formula	C9H8F3NO3
Molecular Weight	235.16 g/mol
Synonyms	4-Nitro-1-ethoxy-2-(trifluoromethyl)benzene; 2-Ethoxy-5-nitrobenzotrifluoride; 5-Nitro-2-(trifluoromethyl)phenetole; 1-Ethoxy-4-nitro-2-trifluoromethylbenzene; 2-Trifluoromethyl-4-nitrophenetole; Benzene, 1-ethoxy-4-nitro-2-(trifluoromethyl)-; 5-Nitro-α,α,α-trifluoro-o-phenetole
EINECS	Contact for details

Quality Control

Our 1-Ethoxy-4-Nitro-2-(Trifluoromethyl)Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.